Manager David Moyes is returning to his former club as Manchester United Football Club
Here is everything you need to know before watching the match.
The next match between Manchester United and West Ham will occur on Sunday.
Manchester United and West Ham have head-to-head scores.
The first match between Manchester United and West Ham was played on February 25, 1911.
It ended with a 2-1 score and a victory for the Hammers
at Upton Park.
The victory was on the same ground in Old Division Two.
It was the day after a 2-1 loss to Manchester United at Old Trafford.
Manchester United and West Ham have faced each other in 149 games.
Seventy one of which were won by Manchester United, while West Ham won 46, and the rest were draws.